Human Reproductive System

Implantation

  • The mitotic division (cleavage) starts as the zygote moves through the isthmus towards the uterus and forms 2, 4, 8, 16 daughter cells called blastomeres.
  • The embryo with 8-16 blastomeres is called a morula.
  • Morula continues to divide and transforms into blastocyst.
  • The blastomeres in the blastocyst are arranged into an outer layer (trophoblast) and an inner group of cells (inner cell mass) attached to trophoblast.
  •  The trophoblast layer then gets attached to endometrium and the inner cell mass gets differentiated to 3 germ layers (outer ectoderm, middle mesoderm & inner endoderm).
  • This 3-layered structure (gastrula) forms the embryo.
  • After attachment, uterine cells divide rapidly and cover the blastocyst. As a result, the blastocyst becomes embedded in the endometrium. This is called implantation.
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